diff --git a/Modules/Compiler/GNU-ASM.cmake b/Modules/Compiler/GNU-ASM.cmake
index e07401d54f..ac241ed2f0 100644
--- a/Modules/Compiler/GNU-ASM.cmake
+++ b/Modules/Compiler/GNU-ASM.cmake
@@ -4,3 +4,7 @@ include(Compiler/GNU)
 set(CMAKE_ASM_SOURCE_FILE_EXTENSIONS s;S;asm)
 
 __compiler_gnu(ASM)
+
+if(CMAKE_ASM${ASM_DIALECT}_COMPILER_ID_VENDOR_MATCH STREQUAL "GNU assembler")
+  set(CMAKE_DEPFILE_FLAGS_ASM${ASM_DIALECT} "--MD <DEPFILE>")
+endif()
diff --git a/Tests/RunCMake/BuildDepends/GNU-AS-stdout.txt b/Tests/RunCMake/BuildDepends/GNU-AS-stdout.txt
new file mode 100644
index 0000000000..c4326ae941
--- /dev/null
+++ b/Tests/RunCMake/BuildDepends/GNU-AS-stdout.txt
@@ -0,0 +1,4 @@
+-- The ASM compiler identification is GNU
+-- Found assembler: [^
+]*/as(\.exe)?
+-- CMAKE_ASM_COMPILER_ID_VENDOR_MATCH='GNU assembler'
diff --git a/Tests/RunCMake/BuildDepends/GNU-AS.cmake b/Tests/RunCMake/BuildDepends/GNU-AS.cmake
new file mode 100644
index 0000000000..21921ef18b
--- /dev/null
+++ b/Tests/RunCMake/BuildDepends/GNU-AS.cmake
@@ -0,0 +1,13 @@
+enable_language(ASM)
+
+# Validate undocumented implementation detail.
+message(STATUS "CMAKE_ASM${ASM_DIALECT}_COMPILER_ID_VENDOR_MATCH='${CMAKE_ASM${ASM_DIALECT}_COMPILER_ID_VENDOR_MATCH}'")
+
+add_library(gnu_as STATIC gnu_as.s)
+target_include_directories(gnu_as PRIVATE ${CMAKE_CURRENT_BINARY_DIR})
+
+file(GENERATE OUTPUT ${CMAKE_CURRENT_BINARY_DIR}/check-$<LOWER_CASE:$<CONFIG>>.cmake CONTENT "
+set(check_pairs
+  \"$<TARGET_FILE:gnu_as>|${CMAKE_CURRENT_BINARY_DIR}/gnu_as.inc\"
+  )
+")
diff --git a/Tests/RunCMake/BuildDepends/GNU-AS.step1.cmake b/Tests/RunCMake/BuildDepends/GNU-AS.step1.cmake
new file mode 100644
index 0000000000..15a5e96bac
--- /dev/null
+++ b/Tests/RunCMake/BuildDepends/GNU-AS.step1.cmake
@@ -0,0 +1 @@
+file(WRITE "${RunCMake_TEST_BINARY_DIR}/gnu_as.inc" "")
diff --git a/Tests/RunCMake/BuildDepends/GNU-AS.step2.cmake b/Tests/RunCMake/BuildDepends/GNU-AS.step2.cmake
new file mode 100644
index 0000000000..15a5e96bac
--- /dev/null
+++ b/Tests/RunCMake/BuildDepends/GNU-AS.step2.cmake
@@ -0,0 +1 @@
+file(WRITE "${RunCMake_TEST_BINARY_DIR}/gnu_as.inc" "")
diff --git a/Tests/RunCMake/BuildDepends/RunCMakeTest.cmake b/Tests/RunCMake/BuildDepends/RunCMakeTest.cmake
index 14ae2439b7..753417dab7 100644
--- a/Tests/RunCMake/BuildDepends/RunCMakeTest.cmake
+++ b/Tests/RunCMake/BuildDepends/RunCMakeTest.cmake
@@ -103,3 +103,8 @@ endfunction()
 if(RunCMake_GENERATOR STREQUAL "Xcode")
   run_ReGeneration(regenerate-project)
 endif()
+
+if(CMake_TEST_BuildDepends_GNU_AS)
+  set(ENV{ASM} "${CMake_TEST_BuildDepends_GNU_AS}")
+  run_BuildDepends(GNU-AS)
+endif()
diff --git a/Tests/RunCMake/BuildDepends/gnu_as.s b/Tests/RunCMake/BuildDepends/gnu_as.s
new file mode 100644
index 0000000000..a2e7dfb0d3
--- /dev/null
+++ b/Tests/RunCMake/BuildDepends/gnu_as.s
@@ -0,0 +1 @@
+.include "gnu_as.inc"
diff --git a/Tests/RunCMake/CMakeLists.txt b/Tests/RunCMake/CMakeLists.txt
index 4b5475edb1..f99f704ca0 100644
--- a/Tests/RunCMake/CMakeLists.txt
+++ b/Tests/RunCMake/CMakeLists.txt
@@ -169,7 +169,20 @@ if(CMake_TEST_Qt5 AND Qt5Widgets_FOUND)
   set(autogen_with_qt5 TRUE)
 endif ()
 add_RunCMake_test(Autogen -Dwith_qt5=${autogen_with_qt5})
-add_RunCMake_test(BuildDepends)
+if(NOT DEFINED CMake_TEST_BuildDepends_GNU_AS
+    AND CMAKE_C_COMPILER_ID STREQUAL "GNU"
+    AND CMAKE_GENERATOR MATCHES "^Ninja"
+    )
+  execute_process(COMMAND "${CMAKE_C_COMPILER}" -print-prog-name=as
+    RESULT_VARIABLE _gnu_res
+    OUTPUT_VARIABLE _gnu_as OUTPUT_STRIP_TRAILING_WHITESPACE ERROR_QUIET)
+  if(_gnu_res EQUAL 0 AND _gnu_as)
+    set(CMake_TEST_BuildDepends_GNU_AS "${_gnu_as}")
+  endif()
+endif()
+add_RunCMake_test(BuildDepends
+  -DCMake_TEST_BuildDepends_GNU_AS=${CMake_TEST_BuildDepends_GNU_AS}
+  )
 if(UNIX AND "${CMAKE_GENERATOR}" MATCHES "Unix Makefiles|Ninja")
   add_RunCMake_test(Byproducts)
 endif()